diff --git a/sound/usb/quirks-table.h b/sound/usb/quirks-table.h
index 4f56e1784932a29e21d92ee6508b6b54030d7164..853da162fd18c38df1299e7fe5d50a733f54dadd 100644
--- a/sound/usb/quirks-table.h
+++ b/sound/usb/quirks-table.h
@@ -3802,6 +3802,54 @@ YAMAHA_DEVICE(0x7010, "UB99"),
 	}
 },
 
+/*
+ * MacroSilicon MS2100/MS2106 based AV capture cards
+ *
+ * These claim 96kHz 1ch in the descriptors, but are actually 48kHz 2ch.
+ * They also need QUIRK_FLAG_ALIGN_TRANSFER, which makes one wonder if
+ * they pretend to be 96kHz mono as a workaround for stereo being broken
+ * by that...
+ *
+ * They also have an issue with initial stream alignment that causes the
+ * channels to be swapped and out of phase, which is dealt with in quirks.c.
+ */
+{
+	USB_AUDIO_DEVICE(0x534d, 0x0021),
+	.driver_info = (unsigned long) &(const struct snd_usb_audio_quirk) {
+		.vendor_name = "MacroSilicon",
+		.product_name = "MS210x",
+		.ifnum = QUIRK_ANY_INTERFACE,
+		.type = QUIRK_COMPOSITE,
+		.data = &(const struct snd_usb_audio_quirk[]) {
+			{
+				.ifnum = 2,
+				.type = QUIRK_AUDIO_STANDARD_MIXER,
+			},
+			{
+				.ifnum = 3,
+				.type = QUIRK_AUDIO_FIXED_ENDPOINT,
+				.data = &(const struct audioformat) {
+					.formats = SNDRV_PCM_FMTBIT_S16_LE,
+					.channels = 2,
+					.iface = 3,
+					.altsetting = 1,
+					.altset_idx = 1,
+					.attributes = 0,
+					.endpoint = 0x82,
+					.ep_attr = USB_ENDPOINT_XFER_ISOC |
+						USB_ENDPOINT_SYNC_ASYNC,
+					.rates = SNDRV_PCM_RATE_CONTINUOUS,
+					.rate_min = 48000,
+					.rate_max = 48000,
+				}
+			},
+			{
+				.ifnum = -1
+			}
+		}
+	}
+},
+
 /*
  * MacroSilicon MS2109 based HDMI capture cards
  *
diff --git a/sound/usb/quirks.c b/sound/usb/quirks.c
index 12ce69b04f634cf89a5331af52b9ecf92602255f..a7bcae0a2c75b43ce94500e0421f476172bb13ed 100644
--- a/sound/usb/quirks.c
+++ b/sound/usb/quirks.c
@@ -1478,6 +1478,7 @@ void snd_usb_set_format_quirk(struct snd_usb_substream *subs,
 	case USB_ID(0x041e, 0x3f19): /* E-Mu 0204 USB */
 		set_format_emu_quirk(subs, fmt);
 		break;
+	case USB_ID(0x534d, 0x0021): /* MacroSilicon MS2100/MS2106 */
 	case USB_ID(0x534d, 0x2109): /* MacroSilicon MS2109 */
 		subs->stream_offset_adj = 2;
 		break;
@@ -1908,6 +1909,8 @@ static const struct usb_audio_quirk_flags_table quirk_flags_table[] = {
 		   QUIRK_FLAG_IGNORE_CTL_ERROR),
 	DEVICE_FLG(0x413c, 0xa506, /* Dell AE515 sound bar */
 		   QUIRK_FLAG_GET_SAMPLE_RATE),
+	DEVICE_FLG(0x534d, 0x0021, /* MacroSilicon MS2100/MS2106 */
+		   QUIRK_FLAG_ALIGN_TRANSFER),
 	DEVICE_FLG(0x534d, 0x2109, /* MacroSilicon MS2109 */
 		   QUIRK_FLAG_ALIGN_TRANSFER),
 	DEVICE_FLG(0x1224, 0x2a25, /* Jieli Technology USB PHY 2.0 */