Swapped 5.1 channels
After installing PW on my Fedora Rawhide, the RR/RL are swapped with CEN/SUB. Swapping the audiojacks fixes the issue, but they are now certainly plugged in in wrong order. This appears to be similar to #445 (closed).
$ rpm -q pipewire-pulseaudio
pipewire-pulseaudio-0.3.22-7.fc35.x86_64